Criteria & Principles
Primaquine may be used as an alternative agent for the treatment of Pneumocystis pneumonia (PJP) when administered in combination with clindamycin
Usual Dose & Administration
30 mg base (52.6 mg salt) PO once daily
Drug-Specific Information
**Dosages customarily expressed in terms of primaquine base, however tablets are available in salt form. Use caution when ordering correct dose**
General Notes
- Up-to-date cost information, click here
- IV antimicrobials outpatient (OPAT) dosing, click here
- Obesity dosing weight recommendations here
- Helpful drug-drug interaction check website here
- When dosing guidance is provided it is important to note the following:
Fixed (ie non weight-based) doses in adults are historically based on a 70 kg patient. Specific disease states or individual patients may warrant dosages that differ from the above recommendations. Since product-specific criteria for dose adjustment based on creatinine clearance exist, consult product information regarding specific recommendations for dosage adjustment based on estimated creatinine clearance.